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    <admin>
        <current_status>
            <date>2024-05-08</date>
            <code>REL</code>
            <processing_site>PDBe</processing_site>
        </current_status>
        <sites>
            <deposition>PDBj</deposition>
            <last_processing>PDBe</last_processing>
        </sites>
        <key_dates>
            <deposition>2022-10-26</deposition>
            <header_release>2024-05-08</header_release>
            <map_release>2024-05-08</map_release>
            <update>2024-05-08</update>
        </key_dates>
        <grant_support>
            <grant_reference>
                <funding_body>Department of Biotechnology (DBT, India)</funding_body>
                <code>BT/INF/22/SP22844/2017</code>
                <country>India</country>
            </grant_reference>
            <grant_reference>
                <funding_body>Science and Engineering Research Board (SERB)</funding_body>
                <code>SERB-EMR/2016/000608 and SERB-IPA/2020/000094</code>
                <country>India</country>
            </grant_reference>
            <grant_reference>
                <funding_body>Bill &amp; Melinda Gates Foundation</funding_body>
                <code>INV-030592</code>
                <country>United States</country>
            </grant_reference>
            <grant_reference>
                <funding_body>Department of Biotechnology (DBT, India)</funding_body>
                <code>IA/TSG/19/1/600019</code>
                <country>India</country>
            </grant_reference>
        </grant_support>
        <title>State - II: Spike 3-up RBD with THSC20.HVTR26 (Fab26)</title>
        <authors_list>
            <author ORCID="0000-0001-6949-4000">Rencilin CF</author>
            <author>Ansari MY</author>
            <author ORCID="0000-0002-4089-8252">Chatterjee A</author>
            <author>Deshpande S</author>
            <author>Mukherjee S</author>
            <author>Singh R</author>
            <author>Jayatheertha S</author>
            <author>Reddy PM</author>
            <author>Das P</author>
            <author>Hingankar N</author>
            <author>Rathore D</author>
            <author>Varadarajan R</author>
            <author ORCID="0000-0002-1531-3822">Bhattacharya J</author>
            <author ORCID="0000-0002-3181-0108">Dutta S</author>
        </authors_list>
        <keywords>Monoclonal antibodies, SARS-CoV-2, Cryo-EM, IMMUNE SYSTEM</keywords>
    </admin>
    <crossreferences>
        <citation_list>
            <primary_citation>
                <journal_citation published="false">
                    <author ORCID="0000-0001-6949-4000" order="1">Rencilin CF</author>
                    <author order="2">Ansari MY</author>
                    <author ORCID="0000-0002-4089-8252" order="3">Chatterjee A</author>
                    <author order="4">Deshpande S</author>
                    <author order="5">Mukherjee S</author>
                    <author order="6">Singh R</author>
                    <author order="7">Jayatheertha S</author>
                    <author order="8">Reddy PM</author>
                    <author order="9">Das P</author>
                    <author order="10">Hingankar N</author>
                    <author order="11">Rathore D</author>
                    <author order="12">Varadarajan R</author>
                    <author ORCID="0000-0002-1531-3822" order="13">Bhattacharya J</author>
                    <author ORCID="0000-0002-3181-0108" order="14">Dutta S</author>
                    <title>State - I: Spike 2-up RBD with THSC20.HVTR26 (Fab26)</title>
                    <journal_abbreviation>To Be Published</journal_abbreviation>
                    <external_references type="CSD">0353</external_references>
                </journal_citation>
            </primary_citation>
        </citation_list>
    </crossreferences>
    <sample>
        <name>Wuhan SARS-CoV-2 Spike trimer complex with THSC20.HVTR26 (Fab26) [State II - 3-up RBD]</name>
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            <complex_supramolecule supramolecule_id="1">
                <name>Wuhan SARS-CoV-2 Spike trimer complex with THSC20.HVTR26 (Fab26) [State II - 3-up RBD]</name>
                <parent>0</parent>
                <natural_source database="NCBI">
                    <organism ncbi="2697049">Severe acute respiratory syndrome coronavirus 2</organism>
                    <strain>wuhan</strain>
                </natural_source>
            </complex_supramolecule>
            <complex_supramolecule supramolecule_id="2">
                <name>THSC20.HVTR26(Fab26)</name>
                <parent>1</parent>
                <natural_source database="NCBI">
                    <organism ncbi="9606">Homo sapiens</organism>
                </natural_source>
            </complex_supramolecule>
            <complex_supramolecule supramolecule_id="3">
                <name>Wuhan SARS-CoV-2 Spike protein</name>
                <parent>1</parent>
                <natural_source database="NCBI">
                    <organism ncbi="2697049">Severe acute respiratory syndrome coronavirus 2</organism>
                    <strain>Wuhan</strain>
                </natural_source>
            </complex_supramolecule>
        </supramolecule_list>
    </sample>
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                <single_particle_preparation preparation_id="1">
                    <buffer>
                        <ph>7.4</ph>
                    </buffer>
                    <vitrification>
                        <cryogen_name>ETHANE</cryogen_name>
                    </vitrification>
                </single_particle_preparation>
            </specimen_preparation_list>
            <microscopy_list>
                <single_particle_microscopy microscopy_id="1">
                    <microscope>FEI TALOS ARCTICA</microscope>
                    <illumination_mode>OTHER</illumination_mode>
                    <imaging_mode>BRIGHT FIELD</imaging_mode>
                    <electron_source>FIELD EMISSION GUN</electron_source>
                    <acceleration_voltage units="kV">200</acceleration_voltage>
                    <nominal_defocus_min units="µm">1.25</nominal_defocus_min>
                    <nominal_defocus_max units="µm">2.75</nominal_defocus_max>
                    <image_recording_list>
                        <image_recording image_recording_id="1">
                            <film_or_detector_model>GATAN K2 SUMMIT (4k x 4k)</film_or_detector_model>
                            <detector_mode>COUNTING</detector_mode>
                            <average_electron_dose_per_image units="e/Å^2">45.0</average_electron_dose_per_image>
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                    </image_recording_list>
                </single_particle_microscopy>
            </microscopy_list>
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                <image_recording_id>1</image_recording_id>
                <startup_model type_of_model="EMDB MAP">
                    <emdb_id>EMD-31100</emdb_id>
                </startup_model>
                <final_reconstruction>
                    <resolution units="Å" res_type="BY AUTHOR">4.8</resolution>
                    <resolution_method>FSC 0.143 CUT-OFF</resolution_method>
                    <number_images_used>48584</number_images_used>
                </final_reconstruction>
                <initial_angle_assignment>
                    <type>MAXIMUM LIKELIHOOD</type>
                </initial_angle_assignment>
                <final_angle_assignment>
                    <type>MAXIMUM LIKELIHOOD</type>
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            <b units="Å">331.2</b>
            <c units="Å">331.2</c>
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        <label>::::EMDATABANK.org::::EMD-34603::::</label>
        <annotation_details>State - II: Spike 3-up RBD with THSC20.HVTR26 (Fab26)</annotation_details>
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                    <row>360</row>
                    <sec>360</sec>
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                    <a units="Å">331.2</a>
                    <b units="Å">331.2</b>
                    <c units="Å">331.2</c>
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                    <beta units="deg">90.0</beta>
                    <gamma units="deg">90.0</gamma>
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                <label>::::EMDATABANK.org::::EMD-34603::::</label>
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                <dimensions>
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                    <minimum>-0.018226529</minimum>
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                <label>::::EMDATABANK.org::::EMD-34603::::</label>
                <annotation_details>State - II: Spike 3-up RBD with THSC20.HVTR26 (Fab26) Half map 2</annotation_details>
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