2025-07-02 REL PDBe INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY EXPERIMENTAL_SUMMARY em_admin em_software _em_admin.last_update _em_software.name DATABASE_REFERENCES citation citation_author _citation.pdbx_database_id_PubMed _citation.title _citation_author.identifier_ORCID DATABASE_REFERENCES citation _citation.journal_volume _citation.page_first _citation.page_last STRUCTURE_SUMMARY chem_comp_atom chem_comp_bond database_2 em_admin pdbx_entry_details pdbx_modification_feature _database_2.pdbx_DOI _database_2.pdbx_database_accession _em_admin.last_update _pdbx_entry_details.has_protein_modification DATA_COLLECTION em_admin em_software _em_admin.last_update _em_software.name PDBe PDBe 2020-09-01 2020-09-16 2020-09-16 2025-07-02 The Francis Crick Institute FC001078 United Kingdom The Francis Crick Institute FC001143 United Kingdom SARS-CoV-2 Spike Glycoprotein with 1 ACE2 Bound Benton DJ Wrobel AG SARS-CoV-2, Spike, Virus Glycoprotein, Coronavirus, VIRAL PROTEIN, ACE2 Benton DJ Wrobel AG Xu P Roustan C Martin SR Rosenthal PB Skehel JJ Gamblin SJ Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion. Nature UK 588 327 330 2020 32942285 doi:10.1038/s41586-020-2772-0 1476-4687 0006 NATUAS 7a94 FULLOVERLAP SARS-CoV-2 Spike bound to ACE2 SARS-CoV-2 Spike bound to ACE2 0 1 2 Spike glycoprotein 1 1 Severe acute respiratory syndrome coronavirus 2 Angiotensin-converting enzyme 2 1 2 Homo sapiens Spike glycoprotein Severe acute respiratory syndrome coronavirus 2 0.142410078 3 Homo sapiens LEVO MGILPSPGMPALLSLVSLLSVLLMGCVAETGMFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLH STQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIK VCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTP INLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAV DCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLY NSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNY NYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKK STNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVA VLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRRARSVAS QSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTG IAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDL ICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNS AIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDPPEAEVQIDRLITGRLQSLQTYVT QQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHF PREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDI SGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQSGRENLYFQGGGGSGYIPEAPRDGQAYVRKDGEWVLLSTFL GHHHHHH P0DTC2 Angiotensin-converting enzyme 2 Homo sapiens 0.075337422 1 Homo sapiens LEVO METDTLLLWVLLLWVPGSTGSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQST LAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDY NERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYE HLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSV GLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANE GFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWW EMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNML RLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADDYKDDDDKWSHPQFEKGGGSGGG SGGSSAWSHPQFEK Q9BYF1 3.4.17.23 2-acetamido-2-deoxy-beta-D-glucopyranose 0.000221208 23 NAG ZINC ION 6.5409e-05 1 ZN singleParticle particle 8.0 ETHANE FEI VITROBOT MARK III FEI TITAN KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 1.5 3.0 FEI TITAN KRIOS AUTOGRID HOLDER NITROGEN GIF Quantum LS 20 GATAN K2 QUANTUM (4k x 4k) COUNTING 8.0 54.4 1 CTFFIND 4.1.10 PHASE FLIPPING AND AMPLITUDE CORRECTION cryoSPARC Ab Initio C1 3.9 FSC 0.143 CUT-OFF cryoSPARC 2.15 83000 MAXIMUM LIKELIHOOD MAXIMUM LIKELIHOOD cryoSPARC 2.15 emd_11684.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 512 512 512 0 0 0 512 512 512 551.936 551.936 551.936 90.0 90.0 90.0 X Y Z -0.90893424 2.4990482 0.002173234 0.031328265 1.078 1.078 1.078 0.2 AUTHOR OTHER REAL emd_11684_msk_1.map emd_11684_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 512 512 512 0 0 0 512 512 512 551.936 551.936 551.936 90.0 90.0 90.0 X Y Z -2.1064036 2.3674395 0.0011804814 0.2598197 1.078 1.078 1.078 AUTHOR emd_11684_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 512 512 512 0 0 0 512 512 512 551.936 551.936 551.936 90.0 90.0 90.0 X Y Z -2.277843 2.1435366 0.0011779828 0.25985467 1.078 1.078 1.078 AUTHOR