2025-10-29 REL PDBj INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY EXPERIMENTAL_SUMMARY em_admin em_software _em_admin.last_update _em_software.name DATA_COLLECTION em_admin em_software _em_admin.last_update _em_software.name DATABASE_REFERENCES citation citation_author em_admin _citation.country _citation.journal_abbrev _citation.journal_id_CSD _citation.journal_id_ISSN _citation.journal_volume _citation.page_first _citation.page_last _citation.title _citation.year _em_admin.last_update PDBj PDBj 2023-10-10 2024-10-16 2024-10-16 2025-10-29 Not funded Cryo-EM structure of SARS-CoV-2 receptor-binding domain (RBD) complexed with CB6 mutant,S309, and S304 antibodies Su C Qi JX Gao GF SARS-CoV-2, RBD, CB6, receptor-binding domain, etesevimab, mutant, VIRAL PROTEIN, IMMUNE SYSTEM-VIRAL PROTEIN complex Su C He J Xie Y Hu Y Li X Qiao S Liu P Huang M Zhang R Wang L Chang Z Sun W Xu K Zhang J Cao L Han P Zhao X Qi J Wang Q Yang M Gao GF Enabling the immune escaped etesevimab fully-armed against SARS-CoV-2 Omicron subvariants including KP.2 Hlife CN 3 132 145 2025 2949-9283 8wpy FULLOVERLAP EMDB EMD-37726 associated EM volume
Cryo-EM structure of SARS-CoV-2 receptor-binding domain (RBD) complexed with CB6 mutant,S309, and S304 antibodies
 Cryo-EM structure of SARS-CoV-2 receptor-binding domain (RBD) complexed with CB6 mutant,S309, and S304 antibodies Cryo-EM structure of SARS-CoV-2 receptor-binding domain (RBD) complexed with CB6 mutant,S309, and S304 antibodies 0 1 2 3 4 5 6 7 Homo sapiens fab 1 1 2 3 4 5 6 Severe acute respiratory syndrome-related coronavirus SARS-CoV-2 RBD 1 7 S309 fab heavy chain Homo sapiens 0.025747725 1 Homo sapiens LEVO QVQLVQSGAEVKKPGASVKVSCKASGYPFTSYGISWVRQAPGQGLEWMGWISTYNGNTNYAQKFQGRVTMTTDTSTTTGY MELRRLRSDDTAVYYCARDYTRGAWFGESLIGGFDNWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYF PEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHHHHHH S309 fab light chain Homo sapiens 0.023291776999999996 1 Homo sapiens LEVO EIVLTQSPGTLSLSPGERATLSCRASQTVSSTSLAWYQQKPGQAPRLLIYGASSRATGIPDRFSGSGSGTDFTLTISRLE PEDFAVYYCQQHDTSLTFGGGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECS CB6 fab mutant heavy chain Homo sapiens 0.024862911999999997 1 Homo sapiens LEVO EVQLVESGGGLVQPGGSLRLSCAASEFIVSYNYMSWVRQAPGKGLEWVSVIYPGGSTFYADSVKGRFTISRDNSMNTLFL QMNSLRAEDTAVYYCARVLPINGYYLDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSW NSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHHHHHH CB6 fab mutant light chain Homo sapiens 0.023559068 1 Homo sapiens LEVO DIVMTQSPSSLSASVGDRVTITCRASQSIAYYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQP EDFATYYCQQSSDPPEYTFGQGTKLEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECS S304 fab heavy chain Homo sapiens 0.02493067 1 Homo sapiens LEVO QVQLVESGGGLVQPGGSLRLSCAASGFTFSSYDMHWVRQTTGKGLEWVSTIGTAGDTYYPDSVKGRFTISREDAKNSLYL QMNSLRAGDTAVYYCARGDSSGYYYYFDYWGQGTLLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVS WNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKTHHHHHH S304 fab light chain Homo sapiens 0.023457025 1 Homo sapiens LEVO DIQMTQSPSSLSAAVGDRVTITCRASQSIGSYLNWYQQKPGKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQP EDFAIYYCQQSYVSPTYTFGPGTKVDIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNS QESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECS Spike protein S1 Severe acute respiratory syndrome coronavirus 2 0.025951219 1 Homo sapiens LEVO RVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYAD SFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGST PCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFHHHHHH P0DTC2 singleParticle particle 8.0 ETHANE FEI TITAN KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 1.0 2.0 GATAN K3 (6k x 4k) 50.0 1 PHASE FLIPPING ONLY 7X1M 3.02 FSC 0.143 CUT-OFF 205618 MAXIMUM LIKELIHOOD MAXIMUM LIKELIHOOD emd_37726.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 360 360 360 0 0 0 360 360 360 306.0 306.0 306.0 90.0 90.0 90.0 X Y Z -0.0017791468 1.790874 0.0007771919 0.019163186 0.85 0.85 0.85 0.0045 AUTHOR emd_37726_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 360 360 360 0 0 0 360 360 360 306.0 306.0 306.0 90.0 90.0 90.0 X Y Z -0.42252842 1.2720481 0.00079984055 0.039370168 0.85 0.85 0.85 AUTHOR emd_37726_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 360 360 360 0 0 0 360 360 360 306.0 306.0 306.0 90.0 90.0 90.0 X Y Z -0.48875326 1.2571161 0.0008066697 0.039489474 0.85 0.85 0.85 AUTHOR