2025-10-01 REL RCSB INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY DATABASE_REFERENCES citation citation_author em_admin _citation.country _citation.journal_abbrev _citation.journal_id_ASTM _citation.journal_id_CSD _citation.journal_id_ISSN _citation.journal_volume _citation.pdbx_database_id_DOI _citation.pdbx_database_id_PubMed _citation.title _citation.year _em_admin.last_update RCSB RCSB 2024-05-02 2025-05-07 2025-05-07 2025-10-01 National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID) United States Cryo-EM structure of rhesus antibody 6070-a.01 in complex with HIV-1 Env trimer Q23.17 MD39 Roark RS Shapiro L Kwong PD Neutralizing antibody, HIV-1 V2 apex, SHIV-elicited, Viral protein, IMMUNE SYSTEM, VIRAL PROTEIN-IMMUNE SYSTEM complex Roark RS Habib R Gorman J Li H Connell AJ Bonsignori M Guo Y Hogarty MP Olia AS Sowers KJ Zhang B Bibollet-Ruche F Bylund T Callaghan S Carey JW Cerutti G Harris DR He W Lewis E Liu T Mason RD Qiao Y Park Y Rando JM Singh A Wolff JJ Lei QP Louder MK Andrabi R Doria-Rose NA Saunders KO Seaman MS Haynes BF Kulp DW Mascola JR Roederer M Pierson TC Sheng Z Hahn BH Shaw GM Kwong PD Shapiro L Structural and genetic basis of HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies. J.Exp.Med. US 222 2025 40824240 doi:10.1084/jem.20250638 1540-9538 0774 JEMEAV 9bnl FULLOVERLAP EMDB EMD-44729 associated EM volume
Cryo-EM structure of rhesus antibody 6070-a.01 in complex with HIV-1 Env Q23.17 MD39 SOSIP
 Complex of 6070-a.01 with HIV-1 Q23.17 envelope trimer Complex of 6070-a.01 with HIV-1 Q23.17 envelope trimer 0 1 2 3 4 Macaca mulatta Envelope glycoprotein Gp120 Human immunodeficiency virus 1 0.052382374999999995 3 Homo sapiens LEVO NLWVTVYYGVPVWRDADTTLFCASDAKAYETEKHNVWATHACVPTDPNPQEIHLDNVTEKFNMWKNNMVEQMHEDIISLW DQSLKPCVKLTPLCVTLHCTNVTSVNTTGDREGLKNCSFNMTTELRDKRQKVYSLFYRLDIVPINENQGSEYRLINCNTS AITQACPKVSFEPIPIHYCTPAGFAILKCKDEGFNGTGLCKNVSTVQCTHGIKPVVSTQLLLNGSLAEKNIIIRSENITN NAKIIIVQLVQPVTIKCIRPNNNTVKSIRIGPGQAFYYTGDIIGDIRQAHCNVTRSRWNKTLQEVAEKLRTYFGNKTIIF ANSSGGDLEITTHSFNCGGEFFYCNTSGLFNSTWYVNSTWNDTDSTQESNDTITLPCRIKQIINMWQRAGQAMYAPPIPG VIKCESNITGLLLTRDGGKDNNVNETFRPGGSDMRDNWRSELYKYKVVEIEPLGVAPTRCKRRV O55774 Envelope glycoprotein Gp41 Human immunodeficiency virus 1 0.016291531999999997 3 Homo sapiens LEVO LGFLGAAGSTMGAASITLTVQARNLLSGIVQQQNNLLRAIEAQQHLLKLTHWGIKQLQARVLAVEHYLRDQQLLGIWGCS GKLICCTNVPWNSSWSNKSLDEIWNNMTWLQWDKEINNYTQLIYRLIEESQNQQEKNEKELL O55774 6070-a.01 heavy chain Macaca mulatta 0.014704397000000001 1 Homo sapiens LEVO QVTLKESGPALVKPTQTLTLTCTFSGFSLSTSGMAVGWIRQPPGKALEWLANIYWDGDTYYSTSLKSRLTISKDTSKNQV ALKMTNMDPVDTATYFCARGEESFYEDD(TYS)GQMEWLHSFDAWGQGLRVTVSS 6070-a.01 light chain Macaca mulatta 0.011548873999999999 1 Homo sapiens LEVO DIQMTQSPPSLSASIGDRVTITCRASQGISNYLAWYQQKPGKAPKRLVYDASTLQGGVPSRFSGSGSGTYFSLTISSLQP EDFATYYCLQHNSHPLTFGGGTKVDIK 2-acetamido-2-deoxy-beta-D-glucopyranose 0.000221208 20 NAG singleParticle particle 7.4 ETHANE FEI TITAN KRIOS FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 300 0.8 2.0 GATAN K3 (6k x 4k) 58.0 1 NONE 7LLK 3.6 FSC 0.143 CUT-OFF 62547 NOT APPLICABLE NOT APPLICABLE emd_44729.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 384 384 384 0 0 0 384 384 384 318.72 318.72 318.72 90.0 90.0 90.0 X Y Z -0.11504728 0.38108554 0.0015629113 0.015050944 0.83 0.83 0.83 0.1 AUTHOR emd_44729_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 384 384 384 0 0 0 384 384 384 318.72 318.72 318.72 90.0 90.0 90.0 X Y Z -0.4019399 0.6423811 0.0013379231 0.048765272 0.83 0.83 0.83 AUTHOR emd_44729_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 384 384 384 0 0 0 384 384 384 318.72 318.72 318.72 90.0 90.0 90.0 X Y Z -0.3948934 0.6228337 0.00135479 0.04883175 0.83 0.83 0.83 AUTHOR